Nightlife in Rome
Rome has a wealth of nightlife raging from cozy Irish bars where you'll be able to watch the footy over a pint of Guinness, to hip Italian clubs which stay open well into the early hours.
Hotspots
The favourite hangout of young English-speaking expats in Rome is Campo dei Fiori, right in the centre of Rome. It can get crowded and noisy as the evening progresses, but if that's what you're after, then Campo dei Fiori. The principle clubbing area is Testaccio, to the south of the centre.
Smoking
Smoking is not allowed in enclosed public spaces in Rome. Smokers tend to congregate just outside the bars with their drinks, which can make for a fantastic social atmosphere, but tends to annoy the neighbours. Many nightclubs and bars have outdoor areas where you can smoke.

